EGE UNIVERSITY

Department of Bioengineering Department

Precessor Fluid Technologies and Applications Group

Professor  Özlem Yeşil ÇELİKTAŞ' s Lab

 

             Ege University, Faculty of Engineering

              Bioengineering Department

              35100 Bornova, IZMIR

             Tel: 0232 3115813

             E-posta: ozlem.yesil.celiktas@ege.edu.tr

             Web site:

             https://avesis.ege.edu.tr/ozlem.yesil.celiktas/

                                            https://yesilceliktas.wixsite.com/yesilceliktaslab

 

Area of Expertise

  • Biomimetic microsystems (Organ-on-chips, microfluidic systems, diagnostic kits)
  • Design of drug delivery systems (microfluidic synthesis of nanoparticles, sol-gel synthesis, vesicular systems, niosome, topical formulations)
  • Life science applications of supercritical fluids (decellularization of tissues, processing enzymes, microchip sterilization)

 

Anahtar Sözcükler: Microfluidics, supercritical fluids, biomaterials, hydrogels, nanomaterials

 

Projects

 

  • Synthesis of a novel stiff hydrogel for cartilage tissue engineering functionalized with nanoparticles fabricated by using a microfluidic platform along with in vivo studies. Funded by TUBITAK (117M843), Principle Investigator, (2018-2020).
  • Preparation and in vitro characterization of drug carrier tissue scaffolds by three-dimensional bioprinting for the treatment of bone defects, and its evaluation in the model of in vivo calvarial bone injury. Funded by TUBITAK, 217S365, Researcher, 2018-2021
  • Enzymatic reactions in micro devices with a focus on sol-gel technology: experimental study and model development. Funded by TUBITAK (113M050), Principle Investigator, (2014-2017).
  • Sustainable Polymers from Algae Sugars and Hydrocarbons (SPLASH). Funded by European Union FP7, Principle Investigator of Turkish partner, (2012-2017)

 

 

Publications

  • Rabia Onbas, Ozlem Yesil-Celiktas (2019) Alginate-silica hybrid hydrogel within microfluidic channels for biocatalytic conversion. Engineering in Life Sciences, 19, 37-46.
  • Fatemeh Sharifi, Su Su Htwe, Martina Righi, Hua Liu, Anna Peietralunga, Ozlem Yesil-Celiktas, Sushila Maharjan, Byung-Hyun Cha, Su-Ryon Shin, Mehmet Remzi Dokmeci, Nihal Engin Vrana, Amir Ghaemmaghammi, Ali Khademhosseini, Yu Shrike Zhang (2019) A foreign body response-on-a-chip platform. Advanced Healthcare Materials, 8, 1801425.
  • Ozlem Yesil-Celiktas, Shabir Hassan, Amir K. Miri, Sushila Maharjan, Rawan Al-kharboosh, Alfredo Quiñones-Hinojosa, Yu Shrike Zhang (2018) Mimicking human pathophysiology in organ-on-chip devices. Advanced Biosystems, 2 (10) 180010.
  • Elif Ozdemir-Kaynak, Amina Ann Qutub, Ozlem Yesil-Celiktas (2018) Advances in glioblastoma multiforme treatment: new models for nanoparticle therapy. Frontiers Physiology, 9, Article number 170
  • Seref Akay, Rene Heils, Hoc Khiem Trieu, Irina Smirnova, Ozlem Yesil-Celiktas (2017) An injectable alginate-based hydrogel for microfluidic applications. Carbohydrate Polymers, 161, 228-234.